Lompoc is located on scenic Pacific Coast Highway (California Hwy 1) and Highway 246, 55 miles northwest of Santa Barbara, 155 miles northwest of Los Angeles and 270 miles southeast of San Francisco.
The Lompoc Valley is part of the Central California region. Rolling hills surround the Valley in the north, south and east. The level Valley is open at its western end to the Pacific Coast Shoreline. The Pacific Ocean is only 9 miles from downtown Lompoc.